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Postdoc Positions

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Chemistry


Principal Investigator Chi-Huey Wong
Department: Chemistry
Location: La Jolla, CA
Maildrop: BCC-338
Email application materials to: wong@scripps.edu
URL: http://www.scripps.edu/wong/
Research Description:

Postdoctoral Research Fellowship in the Wong Lab. Research in the Wong lab encompasses a broad spectrum of bioorganic and synthetic chemistry. Development of small molecules targeting RNA and design and synthesis of inhibitors to enzymes and receptors are being performed to investigate how small molecules interact with biologically important molecules and in turn, learn more about the function of those molecules.

Position Requirements: Candidates with Ph.D. training in synthetic organic or chemical biology, especially related to glycoscience will be considered. The research project is concerning with development of inhibitors against drug resistant bacterial transglycosidase and influenza surface enzymes/proteins and design of carbohydrate-based vaccines.

Basic knowledge in basic lab procedures & chemical management practices & safety; basic understanding of protein purification and organic synthesis. Also a basic understanding of all biochemical laboratory equipment. Ability to learn new techniques and following instructions.
Principal Investigator Ram Krishnamurthy
Department: Chemistry
Division: 3
Location: La Jolla, CA
Maildrop: BCC-405
Email application materials to: rkrishna@scripps.edu
URL: http://www.scripps.edu/krishnamurthy/
Research Description:

Postdoctoral Research Fellowship in the Krishnamurthy Lab. Research in the Krishnamurthy lab encompasses a broad spectrum of synthetic chemistry and methodology applied to understanding the chemistry associated with the origins of life. This project involves the investigation of small molecule chemistry under aqueous conditions (green chemistry) and discovery of novel and alternative pathways that contributes to the understanding of chemical evolution.

Position Requirements: Qualified candidates should have a PhD in organic chemistry and be well grounded in analytical techniques. The applicant should have a strong synthetic organic chemistry (an emphasis on methodology) with experience in analytical techniques (especially in 13C-NMR and mass spectroscopy). The applicant is expected to read the following papers (Angew. Chem. Int. Ed. 2011, 50, 8127-8130. J. Am. Chem. Soc. 2012, 134, 3577-3589 J. Am. Chem. Soc. 2013, 135, 13440-1344) as the projects she/he will be involved in will be along these lines. Only those candidates who evince and express a strong interest in this type of approach and project will be considered.

Interested parties should email their CV and a description of their research interests to Prof. Ram Krishnamurthy at rkrishna@scripps.edu and should have three letters of reference forwarded on their behalf. Applicants should, in their cover letter, address what their scientific interests and goals are and how (a) they align with this specific project and (b) this position would help in attaining the long term goals.
Principal Investigator Matt Disney
Department: Chemistry
Location: Jupiter, FL
Email application materials to: disney@scripps.edu
URL: http://www.scripps.edu/research/faculty/disney
Research Description:

The Disney Lab at Scripps Florida has multiple openings for postdoctoral candidates in the area of rational design of small molecules targeting RNA.

The selected candidate(s) will conduct research in using a combination of approaches to rationally design small molecules targeting RNA (J. Am. Chem. Soc. 2012, 134(10): 4731-4742; ACS Chem. Biol. 2012, in press; and, ACS Chem. Biol. 2012, 7(3): 496-505). Several compounds have been successfully developed to target repeating RNA transcripts that cause diseases such as Myotonic Dystrophy, Huntington’s Disease, et cetera. We are seeking qualified individuals to contribute to future developments in this area including: (i) using a library-versus-library screen to identify and annotate RNA-ligand interactions (described in J. Am. Chem. Soc. 2011, 133(26): 10111-10118 and Angew. Chem. Int. Ed. Engl. 2010, 49(22): 3816-3818); (ii) using computationally approaches (RNA structure modeling) to identify new RNA targets for small molecules from human genomic sequence; and, (iii) further develop lead bioactive compounds in a variety of cellular and animal model systems.

Our laboratory is located at The Scripps Research Institute in Jupiter, Florida. Students interested in careers in academia or in industry are well suited for these positions. Scripps Florida houses high throughput screening, DMPK, and other facilities that uniquely position us for translational research.

Position Requirements: Qualified candidates should have a PhD in a related scientific discipline and an established background in Bioorganic Chemistry or Chemical Biology. Previous experience in RNA folding, RNA biochemistry/biophysics, or nucleic acids biochemistry/biophysics would be helpful, but is not essential.

Interested parties should email their CV and a description of their research interests to Prof. Matt Disney at Disney@scripps.edu and should have three letters of reference forwarded on their behalf. More information about this position and the laboratory can be found at http://www.scripps.edu/disney/.
Principal Investigator Brian Paegel
Department: Chemistry
Location: Jupiter, FL
Email application materials to: briandna@scripps.edu
Research Description:

A postdoctoral fellowship is available in synthetic biology, cell-based screening, and lipid bilayer vesicle assembly in the laboratory of Prof. Brian Paegel at The Scripps Research Institute in Jupiter, FL.

Scripps Florida is a dynamic research environment where scientists with both academic and industry experience work collaboratively, ideal for the postdoctoral fellow who is undecided about future career trajectories.

Position Requirements: To be considered, applicants must have a doctoral degree and published expertise in a
subset of fields including microfluidics, liposome/GUV synthesis and analysis, and membrane protein biochemistry.

If you are interested in joining our highly interdisciplinary team, please submit your cover letter, CV and a sample publication to Dr. Brian Paegel, briandna@scripps.edu.
Principal Investigator Kate Carroll
Department: Chemistry
Location: Jupiter, FL
Email application materials to:
URL: http://www.scripps.edu/research/faculty/carroll
Research Description:

The Carroll lab in the Department of Chemistry at Scripps, Florida currently has NIH-funded postdoctoral positions available in the areas of Cellular and Molecular Biology, Chemical Biology and Synthetic Chemistry.

Position Requirements: Candidates should possess a PhD in a related scientific discipline.

Postdoctoral candidates should send an inquiry with their CV and have three references send letters of recommendation to kcarroll@scrippps.edu.

In the application / cover letter, please address the following: (1) What are your scientific goals and interests, and how might your graduate research background be leveraged to create synergy with the strengths of our laboratory? (2) What, if any, are your plans for obtaining postdoctoral fellowship funding? (3) What are your long-term career plans as of today? Complete applications with published experience in the above focus areas will be given priority.