page header image

Postdoc Positions

View by Location: All / California / Florida
Return to List

Chemistry


Principal Investigator Chi-Huey Wong
Department: Chemistry
Location: La Jolla, CA
Maildrop: BCC-338
Email application materials to: wong@scripps.edu
URL: http://www.scripps.edu/wong/
Research Description:

Postdoctoral Research Fellowship in the Wong Lab. Research in the Wong lab encompasses a broad spectrum of bioorganic and synthetic chemistry. Development of small molecules targeting RNA and design and synthesis of inhibitors to enzymes and receptors are being performed to investigate how small molecules interact with biologically important molecules and in turn, learn more about the function of those molecules.

Position Requirements: Candidates with Ph.D. training in synthetic organic or chemical biology, especially related to glycoscience will be considered. The research project is concerning with development of inhibitors against drug resistant bacterial transglycosidase and influenza surface enzymes/proteins and design of carbohydrate-based vaccines.

Basic knowledge in basic lab procedures & chemical management practices & safety; basic understanding of protein purification and organic synthesis. Also a basic understanding of all biochemical laboratory equipment. Ability to learn new techniques and following instructions.
Principal Investigator Ramanarayanan Krishnamurthy
Department: Chemistry
Division: 3
Location: La Jolla, CA
Maildrop: MB-16
Email application materials to: rkrishna@scripps.edu
URL: http://www.scripps.edu/krishnamurthy/
Research Description:

The lab of Dr. Ramanarayanan Krishnamurthy is currently seeking a Postdoctoral Fellow to work in Synthetic organic chemistry. This person will be focusing on synthesis of small molecules and the study of their self-assembly into potential self-replicating structures (J. Am. Chem. Soc. 2013, ASAP. DOI: 10.1021/ja410124v and Angew. Chem. Int. Ed. 2013, 52, 5840-5844.)

To be considered send your CV/Resume to rkrishna@scripps.edu

Position Requirements: Ph.D. Degree. A very good knowledge of working synthetic organic chemistry, laboratory and analytical techniques. A basic understanding of all biophysical laboratory equipment and ability to learn new techniques and following instructions will be required.

Candidates familiar with nucleoside and oligonucleotide chemistry will be given a preference.

Must be available to start by June 1, 2014.
Principal Investigator Matt Disney
Department: Chemistry
Location: Jupiter, FL
Email application materials to: disney@scripps.edu
URL: http://www.scripps.edu/research/faculty/disney
Research Description:

The Disney Lab at Scripps Florida has multiple openings for postdoctoral candidates in the area of rational design of small molecules targeting RNA.

The selected candidate(s) will conduct research in using a combination of approaches to rationally design small molecules targeting RNA (J. Am. Chem. Soc. 2012, 134(10): 4731-4742; ACS Chem. Biol. 2012, in press; and, ACS Chem. Biol. 2012, 7(3): 496-505). Several compounds have been successfully developed to target repeating RNA transcripts that cause diseases such as Myotonic Dystrophy, Huntington’s Disease, et cetera. We are seeking qualified individuals to contribute to future developments in this area including: (i) using a library-versus-library screen to identify and annotate RNA-ligand interactions (described in J. Am. Chem. Soc. 2011, 133(26): 10111-10118 and Angew. Chem. Int. Ed. Engl. 2010, 49(22): 3816-3818); (ii) using computationally approaches (RNA structure modeling) to identify new RNA targets for small molecules from human genomic sequence; and, (iii) further develop lead bioactive compounds in a variety of cellular and animal model systems.

Our laboratory is located at The Scripps Research Institute in Jupiter, Florida. Students interested in careers in academia or in industry are well suited for these positions. Scripps Florida houses high throughput screening, DMPK, and other facilities that uniquely position us for translational research.

Position Requirements: Qualified candidates should have a PhD in a related scientific discipline and an established background in Bioorganic Chemistry or Chemical Biology. Previous experience in RNA folding, RNA biochemistry/biophysics, or nucleic acids biochemistry/biophysics would be helpful, but is not essential.

Interested parties should email their CV and a description of their research interests to Prof. Matt Disney at Disney@scripps.edu and should have three letters of reference forwarded on their behalf. More information about this position and the laboratory can be found at http://www.scripps.edu/disney/.
Principal Investigator Brian Paegel
Department: Chemistry
Location: Jupiter, FL
Email application materials to: briandna@scripps.edu
Research Description:

A postdoctoral fellowship is available in synthetic biology, cell-based screening, and lipid bilayer vesicle assembly in the laboratory of Prof. Brian Paegel at The Scripps Research Institute in Jupiter, FL.

Scripps Florida is a dynamic research environment where scientists with both academic and industry experience work collaboratively, ideal for the postdoctoral fellow who is undecided about future career trajectories.

Position Requirements: To be considered, applicants must have a doctoral degree and published expertise in a
subset of fields including microfluidics, liposome/GUV synthesis and analysis, and membrane protein biochemistry.

If you are interested in joining our highly interdisciplinary team, please submit your cover letter, CV and a sample publication to Dr. Brian Paegel, briandna@scripps.edu.
Principal Investigator Kate Carroll
Department: Chemistry
Location: Jupiter, FL
Email application materials to:
URL: http://www.scripps.edu/research/faculty/carroll
Research Description:

The Carroll lab in the Department of Chemistry at Scripps, Florida currently has NIH-funded postdoctoral positions available in the areas of Cellular and Molecular Biology, Chemical Biology and Synthetic Chemistry.

Position Requirements: Candidates should possess a PhD in a related scientific discipline.

Postdoctoral candidates should send an inquiry with their CV and have three references send letters of recommendation to kcarroll@scrippps.edu.

In the application / cover letter, please address the following: (1) What are your scientific goals and interests, and how might your graduate research background be leveraged to create synergy with the strengths of our laboratory? (2) What, if any, are your plans for obtaining postdoctoral fellowship funding? (3) What are your long-term career plans as of today? Complete applications with published experience in the above focus areas will be given priority.
Principal Investigator Paul Thompson
Department: Chemistry
Location: Jupiter, FL
Email application materials to: pthompso@scripps.edu
URL: http://www.scripps.edu/research/faculty/thompson
Research Description:

We are currently seeking a highly-qualified and motivated postdoctoral fellow with an interest in Enzymology and Chemical Biology. The lab focuses on using a variety of biochemical methods to solve problems at the interface of chemistry, biochemistry, and biology.

Specific project areas include the design, synthesis, and evaluation of inhibitors targeting Protein Arginine Deiminase 4, a histone modifying enzyme that is dysregulated in Rheumatoid Arthritis and Cancer, as well as the identification of citrullinated biomarkers of disease.

Our lab is furnished with new, state-of-the-art equipment and is housed within the Department of Chemistry, at The Scripps Research Institute, Scripps Florida.

Position Requirements: PhD in a relevant discipline and related scientific experience.

To be considered, please send CV, brief description of research interests and contact information of references to Prof. Paul R. Thompson at pthompso@scripps.edu.
Principal Investigator William Roush
Department: Chemistry
Location: Jupiter, FL
Email application materials to: cmills@scripps.edu
URL: http://www.scripps.edu/roush/Roush.html
Research Description:

The Drug Discovery Program at the Scripps Research Institute in Jupiter, Florida has postdoctoral positions available for highly motivated Ph.D. graduate students with extensive organic synthesis expertise. These full-time lab positions are available starting in March 2014.

About us:
The medicinal chemistry group is led by Professor William R. Roush. Our ongoing research programs are headed by three experienced medicinal chemists: Associate Directors Ted Kamenecka, Yangbo Feng, and Thomas Bannister. Their research is focused on various drug discovery projects, including the discovery and optimization of kinase inhibitors, GPCR ligands, and modulators of nuclear hormone receptor activity. In addition, many members of the group participate in the discovery of new chemical probes as part of the NIH’s molecular libraries program. Scripps Florida has in-house assay development, DMPK, and pharmacology to support the drug discovery efforts. We have a state-of-the-art high throughput screening facility to identify leads in important new therapeutic areas.

Our laboratories are housed in three state-of-the art spacious new buildings erected on our permanent campus adjacent to the Florida Atlantic University honors campus in Jupiter, in Northern Palm Beach County, 10 miles north of West Palm Beach, 90 miles north of Miami, 160 miles south of Orlando, and less than 5 miles from spectacular Atlantic coast beaches.

The objective of the Drug Discovery Program at Scripps Florida is to discover, develop, and experimentally validate the usefulness of drug candidates and identify corporate partners to develop lead compounds. We continually seek funding through collaborations and research grants. Scripps Florida is a non-profit institution and is the second campus of the Scripps Research Institute headquartered in La Jolla, California. State, county, and local officials view Scripps as a vehicle to create a significant and lasting biotech/pharmaceutical presence in South Florida. More information about Scripps Florida can be found at our website: http://www.scripps.edu/florida/ In addition to the Drug Discovery Program within the Translational Research Institute, Scripps Florida has strong academic research programs in the Departments of Infectology, Cancer Biology, Metabolism and Aging, Neuroscience, Molecular Therapeutics, and Chemistry, The Institute particularly stresses interdisciplinary collaborative research. Scripps Florida has a graduate program (Ph.D.), part of The Scripps Research Institute’s Kellogg School of Science and Technology.

Position Requirements: Extensive Ph.D. graduate work in multi-step organic synthesis is required, with good laboratory skills and familiarity with modern synthetic techniques and instrumentation (HPLC-MS, HPLC, NMR, chromatography). Strong candidates may also have knowledge and experience in heterocyclic and medicinal chemistry and/or structure-based drug design. Excellent communication skills and interpersonal skills necessary to thrive in a fast-paced team-oriented environment are also required.

Please send CV, research summary, and 3 references to: Carol Mills, Scripps Florida, attn: Medicinal Chemistry Recruiting, 130 Scripps Way #3A2, Jupiter, FL 33458; or preferably by e-mail: cmills@scripps.edu (please include “medicinal chemistry postdoctoral recruiting” in the subject line).