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Postdoc Positions

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Chemistry


Principal Investigator Dr. Peter Schultz
Department: Chemistry
Division: 3
Location: La Jolla, CA
Maildrop: BCC-506
Email application materials to: schultz@scripps.edu
URL: http://www.scripps.edu/schultz/
Research Description:

The research group of Dr. Michael Bollong is seeking a talented Postdoctoral fellow with experience in cell and molecular biology to join a collaborative and interdisciplinary team of scientists focused on small molecule discovery and early stage translational research. Specific research activities include high throughput cell-based screens, molecular and cellular biology, and organismal studies of the effects of novel compounds. Projects involve the elucidation of biologically relevant targets/mechanisms of action and evaluation of the activities of optimized lead molecules in pre-clinical rodent models.

Please note this position will be directly supervised by faculty fellow Dr. Michael Bollong as part of the newly formed TSRI fellows program.

Interested applicants should send their curriculum vitae and contact information for references to Michael Bollong directly at: mbollong@scripps.edu.

Hiring preference given to local applicants.

Position Requirements: Must possess a doctoral degree. A pending doctoral degree may be considered with approval of the Principal Investigator.
EEO Statement: The Scripps Research Institute is an Equal Opportunity Employer. All qualified applicants are encouraged to apply and will receive consideration for employment without regard to race, color, religion, sex, sexual orientation, gender identity, national origin, disability, protected veteran status, or any other legally protected characteristic or status.
Principal Investigator Dr. Kate Carroll
Department: Chemistry
Location: Jupiter, FL
Email application materials to: kcarroll@scripp.edu
URL: http://www.katecarrolllab.com/
Research Description:

Chemistry Postdoctoral position(s) available in the Carroll lab (www.scripps.edu/carroll/) in the Department of Chemistry at The Scripps Research Institute in Jupiter, FL (www.scripps.edu/florida/). The Postdoc will address one of two major themes in the lab: 1. Developing chemical probes to study cellular mechanisms of redox-dependent signaling, and/or 2. Developing small-molecule inhibitors that block sulfur metabolism for preclinical evaluation as antibacterial agents.

Desired Candidate Profile:
• You are holding a PhD in chemistry or related field.
• You have a strong expertise in organic synthesis, with a publication record demonstrating independence in research focus.
• You have the ability to communicate clearly in writing, as well as verbally with a diverse set of collaborators.
• You have a strong team spirit and excellent interpersonal skills.
• You are familiar with cell-based assays and basic molecular biology techniques.
• Applicants with experience in redox chemistry and/or medicinal chemistry are strongly encouraged to apply.

The environment:
Located in Jupiter, Palm Beach County, Scripps Florida provides a rich intellectual environment and cutting-edge facilities for its researchers, who conduct studies at the forefront of basic biomedical science, drug discovery, and technology development.

Position Requirements: Applications will be accepted immediately and candidates will be considered until the position is filled. Completion of a PhD is required by start date.

To be considered, all applicants must submit a cover letter, CV, a one page “Research Statement” describing research experience and how this aligns with the focus of the Carroll group, and the names/phone numbers of three references. A single PDF document should be sent to Prof. Kate Carroll (kcarroll@scripp.edu).

Salary will be commensurate with accomplishment, fit, and experience.
EEO Statement: The Scripps Research Institute is an Equal Opportunity Employer. All qualified applicants are encouraged to apply and will receive consideration for employment without regard to race, color, religion, sex, sexual orientation, gender identity, national origin, disability, protected veteran status, or any other legally protected characteristic or status.
Principal Investigator Dr. Matthew Disney
Department: Chemistry
Location: Jupiter, FL
Email application materials to: Disney@scripps.edu
URL: http://www.scripps.edu/disney/
Research Description:

Multiple postdoctoral positions in RNA chemical biology are available in the Disney group in the Department of Chemistry at The Scripps Research Institute. We are committed to each individual’s development to achieve their short term and long term career goals.
Projects with an emphasis on chemical biology center on development of small molecules that target RNA repeat expansions, the causative agent of many neurological and neuromuscular diseases. In particular, the successful candidate will: (i) design high affinity small molecule binders using the structure of the RNA target, our database of RNA-small molecule interactions, and other computational methods; (ii) fully characterize the molecular recognition of the RNA by the small molecule using biophysical methods; (iii) use optimal compounds to study RNA biology in cells and in vivo; and (iv) expand tools available to manipulate RNA in cells. Candidates with demonstrated experience with the following techniques are highly desirable: mammalian cell culture (patient-derived, iPSCs), RNA-seq, splicing isoform analysis by end point RT-PCR and RT-qPCR, RNA-FISH, high throughput screening methods, and conducting experiments in animal models of disease.
Representative publications in this area from our group include: studying the RNA repeats that cause genetically defined ALS and dementia (see: Neuron. 2014 Sep 3;83(5):1043-50); and developing innovative methods to target the RNAs that cause myotonic muscular dystrophy (see: Nat. Chem. Biol. 2017 Feb;13(2):188-193).

Position Requirements: Successful candidates will have a proven track record of publishing in high impact journals, have experience in nucleic acids, medicinal chemistry, or chemical biology, and can work successfully as a member of a team. An emphasis will be placed on candidates that have a track record of high impact publications. Expertise with RNA-seq data analysis and chemical and structural biology is highly desired.

Interested applicants should send their CV and three letters of reference to disney@scripps.edu. A full description of the group’s research focus is available on the web at http://www.scripps.edu/disney/.




EEO Statement: The Scripps Research Institute is an Equal Opportunity Employer. All qualified applicants are encouraged to apply and will receive consideration for employment without regard to race, color, religion, sex, sexual orientation, gender identity, national origin, disability, protected veteran status, or any other legally protected characteristic or status.