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Postdoc Positions

All Postdoc Positions

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Principal Investigator Dr. Matthew Pipkin
Department: Cancer Biology
Location: Jupiter, FL
Email application materials to: mpipkin@scripps.edu
URL: http://www.scripps.edu/research/cancer-biology/index.html
Research Description:

The transcriptional circuitry of CTL differentiation:
A postdoctoral position within the Department of Cancer Biology is available to study the genetic, molecular and cellular basis of effector and memory CD8+ cytotoxic T lymphocyte (CTL) differentiation. The candidate will develop new, and use available, strains of reporter and gene deficient mice to examine the regulation of effector and memory CTL development in response to model infections and tumors. These approaches will be combined with custom retroviral shRNA-miR libraries targeting transcriptional regulators, in the context of infectious models in vivo and simplified in vitro differentiation systems, to discover and dissect the transcriptional circuitry of CTL differentiation. To clarify important questions underlying cell-differentiation, the candidate will apply sophisticated genetic and molecular approaches such as chromosome transfer, BAC recombineering and transgenesis, and next generation sequencing of RNA and DNA derived libraries.

Position Requirements: The ideal candidate will have a Ph.D. in immunology, a strong background in genetics, and extensive experience with flow cytometry and or fluorescent microscopy. In addition, experience with mice and a committed desire to learn and apply classical and cutting-edge molecular biology approaches are strongly desired.

Interested applicants should submit a CV, a brief statement of research skills, experiences, goals, and contact information (email address and phone number) of three references to: mpipkin@scripps.edu.
EEO Statement: The Scripps Research Institute is an Equal Opportunity Employer. All qualified applicants are encouraged to apply and will receive consideration for employment without regard to race, color, religion, sex, sexual orientation, gender identity, national origin, disability, protected veteran status, or any other legally protected characteristic or status.
Principal Investigator Dr. Matthew Pipkin
Department: Cancer Biology
Location: Jupiter, FL
Email application materials to: mpipkin@scripps.edu
URL: http://www.scripps.edu/research/cancer-biology/index.html
Research Description:

The mechanics of nucleosome positioning:
A postdoctoral position within the Department of Cancer Biology is available to study the transcriptional mechanics underlying effector and memory CD8+ T cell differentiation. The candidate’s goals will be to clarify how transcription factor expression levels combined with their affinities for cognate binding sites in DNA control nucleosome positioning and transcription in vivo. The lab has developed and applied novel approaches that integrate bacterial artificial chromosome (BAC) technology and next generation sequencing to map nucleosomes in vivo at unprecedented resolution. A number of genetic tools and approaches are available in the lab to alter expression of essential CD8 T cell specific transcription factors in vitro and in vivo, such as conditional knockout mice, retrovirally expressed cDNAs and whole-genome retroviral shRNA-miR libraries, to examine at the genome-scale how these factors control nucleosome positions and CTL differentiation.

Position Requirements: The ideal candidate will have a Ph.D. in a biological, chemical, or physical science, a quantitative mindset, and a committed desire to learning and applying classical and cutting-edge molecular and biochemical approaches to address the regulation of chromatin and transcription in the immune system.

Interested applicants should submit a CV, a brief statement of research skills, experiences, goals, and contact information (email address and phone number) of three references to: mpipkin@scripps.edu.
EEO Statement: The Scripps Research Institute is an Equal Opportunity Employer. All qualified applicants are encouraged to apply and will receive consideration for employment without regard to race, color, religion, sex, sexual orientation, gender identity, national origin, disability, protected veteran status, or any other legally protected characteristic or status.
Principal Investigator Dr. Tina Izard
Department: Cancer Biology
Location: Jupiter, FL
Email application materials to: cmorrow@scripps.edu
URL: http://www.scripps.edu/florida/cancerbio/izard
Research Description:

Postdoctoral Research Associate positions are immediately available for structure-function studies of cytoskeletal proteins that control signaling downstream of adherens junctions and focal adhesions. Fellows will join an exciting research environment of the Izard laboratory in new state-of-the-art facilities of the Scripps-Florida campus of The Scripps Research Institute (TSRI), which is renowned in the Structural Biology field. The Izard laboratory is recognized as a world leader in the cytoskeleton field.

The position provides an outstanding training program in protein biochemistry and structure, and also in molecular and cellular biology, in a highly dynamic and team-oriented research program. Successful candidates will work in a cutting-edge research environment that tackles this important new arena in cancer and cell biology. The laboratory has outstanding facilities for cell biology, molecular biology, protein expression, purification, and biochemistry, and protein crystallography.

Scripps-Florida provides an incredibly rich scientific environment. Notably, TSRI faculty include an outstanding cadre of senior colleagues, including three Nobel Laureates and about twenty Members of The National Academy of Sciences, including several in crystallography and biophysics. In 2008, Scripps-Florida moved into three new, state-of-the-art research buildings and will expand to eventually house 80 faculty-level investigators. Scripps-Florida has a large cast of outstanding Cores that facilitate basic research and drug development. The unique infrastructure at Scripps-Florida includes the application of unique chemical, genomic, proteomic, informatics, and high-throughput screening and engineering tools for the discovery of novel biomolecules.

Scripps-Florida is a new member of the South East Regional Collaborative Access Team (SER-CAT) that constructed two beam lines at the Advanced Photon Source (APS) at Argonne National Laboratory. The insertion device and bending magnet beam lines are available for all the synchrotron-related data collection needs for the post-doctoral fellows.

Scripps-Florida provides a HighFlux X-ray diffraction system, specifically a Rigaku MicroMax-007 HF, a second-generation true microfocus rotating anode generator. Scripps-Florida also provides an Osmic VariMax optics system and the Proteros Free Mounting System to control the humidity and to optimize diffraction characteristics, including resolution, mosaicity, and anisotropy, as well as reduced X-ray background. Finally, the X-ray laboratory houses the mar345 Image Plate detector.

Palm Beach County is one of the most sought-after communities in the country and offers residents an incomparable lifestyle in a family-friendly community with public playgrounds and parks and access to world-class shopping and unmatched outdoor recreation. It is one of the safest communities in the United States with virtually no crime. The Atlantic Ocean with its 45 miles of spectacular beaches and signature Coconut Palms provides an exclusive getaway in a warm, sunny climate throughout most of the year. There are a number of exquisite art galleries as well as arts and crafts festivals. This golfer’s paradise is also home of the Professional Golfers Association of America (PGA).

Position Requirements: Applicants must have a Ph.D. degree and experience in protein crystallography. Please send CV, a summary of research experience and interests, and names, addresses, e-mail and telephone numbers of 3 references to:

Dr. T. Izard (cmorrow@scripps.edu)
Associate Professor with Tenure
Director, Macromolecular Crystallography Scripps-Florida
Cell Adhesion Laboratory
Department of Cancer Biology
The Scripps Research Institute
Jupiter, FL 33458
EEO Statement: The Scripps Research Institute is an Equal Opportunity Employer. All qualified applicants are encouraged to apply and will receive consideration for employment without regard to race, color, religion, sex, sexual orientation, gender identity, national origin, disability, protected veteran status, or any other legally protected characteristic or status.
Principal Investigator Dr. Katrin Karbstein
Department: Cancer Biology
Location: Jupiter, FL
Email application materials to: kkarbst@scripps.edu
URL: http://www.scripps.edu/karbstein/
Research Description:

Postdoctoral Position in Eukaryotic Ribosome Assembly

Research Description: Funded post-doctoral positions are available in Katrin Karbstein’s laboratory (http://www.scripps.edu/karbstein/) to study regulation and quality control mechanisms during ribosome assembly. Combining a variety of in vitro and in vivo methods with modern systems biology approaches, we are exploring degradation pathways, the causes and effects of defective ribosomes, and other fundamental questions in molecular biology. Being located in the Cancer Biology Department, we are also exploring the links between ribosome assembly and cancer. The laboratory is a supportive, fast-paced environment for driven candidates who enjoy a collaborative atmosphere.

Position Requirements: Applicants with published expertise in yeast genetics and biochemistry, or RNA or protein biochemistry, will be given close consideration. Funding is in place for 3+ years. Please send a cover letter discussing your interests in the laboratory as well as your CV and list of 3 individuals as references to kkarbst@scripps.edu.




EEO Statement: The Scripps Research Institute is an Equal Opportunity Employer. All qualified applicants are encouraged to apply and will receive consideration for employment without regard to race, color, religion, sex, sexual orientation, gender identity, national origin, disability, protected veteran status, or any other legally protected characteristic or status.
Principal Investigator Dr. Peng Wu
Department: Chemical Physiology
Division: 3
Location: La Jolla, CA
Maildrop: MB-208
Email application materials to: pengwu@scripps.edu
URL: http://www.scripps.edu/pwu/index.php/research/
Research Description:

A NIH-funded postdoctoral position is available for highly motivated candidates to study glycosylation in cancer immunology in the laboratory of Prof. Peng Wu, Department of Chemical Physiology, The Scripps Research Institute, La Jolla CA.

Interested candidates should send an application packet, including all of the following as a single PDF file by email to Dr. Peng Wu (pengwu@scripps.edu):
1. Cover letter indicating current and future research interests;
2. Expected starting date;
3. Curriculum vitae;
4. Brief summary of previous research experience (2-3 pages);
5. Names and contact information for 3 references.

Links:

http://www.scripps.edu/pwu/

Position Requirements: Successful candidates will have a recent Ph.D. in chemical biology, glycobiology, cell biology or immunology. Training in multi-color flow cytometry, fluorescent imaging, T-cell or cancer immunology is a plus.
EEO Statement: The Scripps Research Institute is an Equal Opportunity Employer. All qualified applicants are encouraged to apply and will receive consideration for employment without regard to race, color, religion, sex, sexual orientation, gender identity, national origin, disability, protected veteran status, or any other legally protected characteristic or status.
Principal Investigator Dr. Xiang-Lei Yang
Department: Chemical Physiology
Division: 3
Location: La Jolla, CA
Maildrop: BCC-110
Email application materials to: xlyang@scripps.edu
URL: http://www.scripps.edu/yang/
Research Description:

Research Associates are appointed positions for the purpose of developing scholarly competence, working under the supervision of a TSRI Faculty member.

We seek a highly motivated individual to join the Yang laboratory at The Scripps Research Institute as a Postdoctoral Fellow. We are working at the frontier of protein biology associated with novel functions of aminoacyl-tRNA synthetases and with human diseases. Our laboratory provides a multidisciplinary, highly interactive working environment with broad expertise of X-ray crystallography, biochemistry, molecular biology, cell biology, and animal studies. We will provide a unique and challenging opportunity to those who want to succeed. Visit our website at http://www.scripps.edu/yang/ for more information about our laboratory.

Please send resume and cover letter to:
xlyang@scripps.edu

Position Requirements: A recent Ph.D. in molecular and cellular biology or biochemistry is required. A successful applicant should have strong cell and molecular biology expertise, excellent communication skills, and the ability to work independently, collaboratively, and productively with a proven research track record.

Experience in cancer signaling pathway is a strong plus.
EEO Statement: The Scripps Research Institute is an Equal Opportunity Employer. All qualified applicants are encouraged to apply and will receive consideration for employment without regard to race, color, religion, sex, sexual orientation, gender identity, national origin, disability, protected veteran status, or any other legally protected characteristic or status.
Principal Investigator William Balch
Department: Chemical Physiology
Division: 3
Location: La Jolla, CA
Maildrop: MB-6
Email application materials to: webalch@scripps.edu
URL: http://www.scripps.edu/balch/
Research Description:

Position open for an early stage fellow to study the cell and systems biology of human rare disease impacting liver, lung and/or brain function. Interest in membrane biology, protein folding and trafficking through the secretory pathway, and the impact of protein misfolding on human healthspan is of high interest.

Research Associates are appointed positions for the purpose of developing scholarly competence, working under the supervision of a TSRI Faculty member. These appointments are normally not renewed beyond a total of six years. Research Associates cannot apply for external funding either as a Principal Investigator or Co-Principal Investigator without prior approval from a Departmental Chair. Research Associates do not have consulting privileges.

Position Requirements: Must possess a doctoral degree. A pending doctoral degree may be considered with approval of the Principal Investigator.

Knowledge of mammalian tissue culture, biochemical, and cell and molecular techniques essential. Experience with handling of mice considered an asset.

Interested candidates should submit their CV and a list of at least 3 professional references to webalch@scripps.edu or ellab@scripps.edu.
EEO Statement: The Scripps Research Institute is an Equal Opportunity Employer. All qualified applicants are encouraged to apply and will receive consideration for employment without regard to race, color, religion, sex, sexual orientation, gender identity, national origin, disability, protected veteran status, or any other legally protected characteristic or status.
Principal Investigator Dr. Peter Schultz
Department: Chemistry
Division: 3
Location: La Jolla, CA
Maildrop: BCC-506
Email application materials to: schultz@scripps.edu
URL: http://www.scripps.edu/schultz/
Research Description:

The research group of Dr. Michael Bollong is seeking a talented Postdoctoral fellow with experience in cell and molecular biology to join a collaborative and interdisciplinary team of scientists focused on small molecule discovery and early stage translational research. Specific research activities include high throughput cell-based screens, molecular and cellular biology, and organismal studies of the effects of novel compounds. Projects involve the elucidation of biologically relevant targets/mechanisms of action and evaluation of the activities of optimized lead molecules in pre-clinical rodent models.

Please note this position will be directly supervised by faculty fellow Dr. Michael Bollong as part of the newly formed TSRI fellows program.

Interested applicants should send their curriculum vitae and contact information for references to Michael Bollong directly at: mbollong@scripps.edu.

Hiring preference given to local applicants.

Position Requirements: Must possess a doctoral degree. A pending doctoral degree may be considered with approval of the Principal Investigator.
EEO Statement: The Scripps Research Institute is an Equal Opportunity Employer. All qualified applicants are encouraged to apply and will receive consideration for employment without regard to race, color, religion, sex, sexual orientation, gender identity, national origin, disability, protected veteran status, or any other legally protected characteristic or status.
Principal Investigator Dr. Kate Carroll
Department: Chemistry
Location: Jupiter, FL
Email application materials to: kcarroll@scripp.edu
URL: http://www.katecarrolllab.com/
Research Description:

Chemistry Postdoctoral position(s) available in the Carroll lab (www.scripps.edu/carroll/) in the Department of Chemistry at The Scripps Research Institute in Jupiter, FL (www.scripps.edu/florida/). The Postdoc will address one of two major themes in the lab: 1. Developing chemical probes to study cellular mechanisms of redox-dependent signaling, and/or 2. Developing small-molecule inhibitors that block sulfur metabolism for preclinical evaluation as antibacterial agents.

Desired Candidate Profile:
• You are holding a PhD in chemistry or related field.
• You have a strong expertise in organic synthesis, with a publication record demonstrating independence in research focus.
• You have the ability to communicate clearly in writing, as well as verbally with a diverse set of collaborators.
• You have a strong team spirit and excellent interpersonal skills.
• You are familiar with cell-based assays and basic molecular biology techniques.
• Applicants with experience in redox chemistry and/or medicinal chemistry are strongly encouraged to apply.

The environment:
Located in Jupiter, Palm Beach County, Scripps Florida provides a rich intellectual environment and cutting-edge facilities for its researchers, who conduct studies at the forefront of basic biomedical science, drug discovery, and technology development.

Position Requirements: Applications will be accepted immediately and candidates will be considered until the position is filled. Completion of a PhD is required by start date.

To be considered, all applicants must submit a cover letter, CV, a one page “Research Statement” describing research experience and how this aligns with the focus of the Carroll group, and the names/phone numbers of three references. A single PDF document should be sent to Prof. Kate Carroll (kcarroll@scripp.edu).

Salary will be commensurate with accomplishment, fit, and experience.
EEO Statement: The Scripps Research Institute is an Equal Opportunity Employer. All qualified applicants are encouraged to apply and will receive consideration for employment without regard to race, color, religion, sex, sexual orientation, gender identity, national origin, disability, protected veteran status, or any other legally protected characteristic or status.
Principal Investigator Dr. Donna Blackmond
Department: Chemistry
Division: 3
Location: La Jolla, CA
Maildrop: BCC-157
Email application materials to: blackmon@scripps.edu
URL: http://www.scripps.edu/blackmond/
Research Description:

Research Associates are appointed positions for the purpose of developing scholarly competence, working under the supervision of a TSRI Faculty member.

The position involves kinetic and mechanistic studies of innovative new reactions of interest in pharmaceutical process research and development. Projects are carried out in collaboration with scientists at Bristol-Myers Squibb and often involve collaboration with the Baran and Yu laboratories at Scripps.

Please send cover letter and resume to Dr. Donna Blackmond at:
blackmon@scripps.edu

Position Requirements: The ideal candidate has a PhD in organic synthesis and has an interest in kinetics and physical organic chemistry as carried out in pharmaceutical process research and development.

EEO Statement: The Scripps Research Institute is an Equal Opportunity Employer. All qualified applicants are encouraged to apply and will receive consideration for employment without regard to race, color, religion, sex, sexual orientation, gender identity, national origin, disability, protected veteran status, or any other legally protected characteristic or status.
Principal Investigator Dr. Tobin Dickerson
Department: Chemistry
Division: 3
Location: La Jolla, CA
Maildrop: SP-3040
Email application materials to: tobin@scripps.edu
URL: http://www.scripps.edu/dickerson/
Research Description:

Research Associates are appointed positions for the purpose of developing scholarly competence, working under the supervision of a TSRI Faculty member. These appointments are normally not renewed beyond a total of six years. Research Associates cannot apply for external funding either as a Principal Investigator or Co-Principal Investigator without prior approval from a Departmental Chair. Research Associates do not have consulting privileges.

Postdoctoral positions are available immediately in the development of high content screening assays for inhibitors of cellular intoxication. Highly motivated individuals with a Ph.D. in molecular biology, biochemistry, or chemistry are encouraged to apply. Competitive salary and benefit package commensurate with experience will be provided. Interested candidates should submit a curriculum vitae, a statement of research interests, and contact information for three references to:

Tobin J. Dickerson, Ph.D.
Department of Chemistry and Worm Institute for Research and Medicine (WIRM)
The Scripps Research Institute
10550 North Torrey Pines Road, SP30-3040
La Jolla, CA 92037

or by email: tobin@scripps.edu

Position Requirements: Must possess a doctoral degree. A pending doctoral degree may be considered with approval of the Principal Investigator.
EEO Statement: The Scripps Research Institute is an Equal Opportunity Employer. All qualified applicants are encouraged to apply and will receive consideration for employment without regard to race, color, religion, sex, sexual orientation, gender identity, national origin, disability, protected veteran status, or any other legally protected characteristic or status.
Principal Investigator Dr. Matthew Disney
Department: Chemistry
Location: Jupiter, FL
Email application materials to: Disney@scripps.edu
URL: http://www.scripps.edu/disney/
Research Description:

Postdoctoral position in Chemical and Structural Biology of RNA

A postdoctoral position in RNA chemical biology is available in the Disney group in The Department of Chemistry at The Scripps Research Institute (for more information please see: http://www.scripps.edu/disney/). Successful candidates will have a proven track record of publishing in high impact journals and experience in nucleic acids, medicinal chemistry, or chemical biology and can work successfully as a member of a team. An emphasis will be placed on candidates that have published high impact publications.

Position Requirements: The specific focus is on the rational design of small molecules that target RNA for use as both lead therapeutics and chemical probes of function as applied toward diseases that have no known therapeutic or to which there is poor prognosis with current treatments such as inherited neuromuscular diseases such as ALS (see: Neuron. 2014 Sep 3;83(5):1043-50) and Muscular Dystrophy (see: Angew Chem Int Ed Engl. 2014 Oct 6;53(41):10956-9 and ACS Chem Biol. 2013 Oct 18;8(10):2312-21) and highly resistant cancers (see: Nat Chem Biol. 2014 Apr;10(4):291-7). Interested applicants should have their CV and three letters of reference sent to Disney@scripps.edu.
EEO Statement: The Scripps Research Institute is an Equal Opportunity Employer. All qualified applicants are encouraged to apply and will receive consideration for employment without regard to race, color, religion, sex, sexual orientation, gender identity, national origin, disability, protected veteran status, or any other legally protected characteristic or status.
Principal Investigator Brian Paegel
Department: Chemistry
Location: Jupiter, FL
Email application materials to: briandna@scripps.edu
Research Description:

A postdoctoral fellowship is available in synthetic biology, cell-based screening, and lipid bilayer vesicle assembly in the laboratory of Prof. Brian Paegel at The Scripps Research Institute in Jupiter, FL.

Scripps Florida is a dynamic research environment where scientists with both academic and industry experience work collaboratively, ideal for the postdoctoral fellow who is undecided about future career trajectories.

Position Requirements: To be considered, applicants must have a doctoral degree and published expertise in a
subset of fields including microfluidics, liposome/GUV synthesis and analysis, and membrane protein biochemistry.

If you are interested in joining our highly interdisciplinary team, please submit your cover letter, CV and a sample publication to Dr. Brian Paegel, briandna@scripps.edu.
EEO Statement: The Scripps Research Institute is an Equal Opportunity Employer. All qualified applicants are encouraged to apply and will receive consideration for employment without regard to race, color, religion, sex, sexual orientation, gender identity, national origin, disability, protected veteran status, or any other legally protected characteristic or status.
Principal Investigator Dr. Mansun Law
Department: Immunology and Microbial Science
Division: 3
Location: La Jolla, CA
Maildrop: IMM-17
Email application materials to: mlaw@scripps.edu
URL: http://www.scripps.edu/law/
Research Description:

A postdoctoral position is available for a highly motivated individual to study the antibody and B cell responses to hepatitis C infection and vaccination in humans and preclinical animal models including non-human primates. The applicant will join a team of scientists at the recently awarded NIH Hepatitis C Cooperative Center at The Scripps Research Institute to investigate the immunological and genetic basis for the induction of broadly neutralizing antibodies to hepatitis C virus. Background information of the research and research teams can be found at: http://www.scripps.edu/law/ and https://www.scripps.edu/research/faculty/zhu

Position Requirements: Ph.D. in immunology. Strong technical and analytic skills in a broad range of immunological assays to study antibody and B cell responses are required. Experience in single cell technologies, germinal center reaction, and/or antibody repertoire analysis, is a plus. Interested applicants should submit a copy of CV, a brief statement of research skills, goals, and contact information of three professional references (email address and phone number) to mlaw@scripps.edu.
EEO Statement: The Scripps Research Institute is an Equal Opportunity Employer. All qualified applicants are encouraged to apply and will receive consideration for employment without regard to race, color, religion, sex, sexual orientation, gender identity, national origin, disability, protected veteran status, or any other legally protected characteristic or status.
Principal Investigator Dr. Richard Wyatt
Department: Immunology and Microbial Science
Division: 3
Location: La Jolla, CA
Maildrop: IMM-28
Email application materials to: wyatt@scripps.edu
URL: http://www.scripps.edu/wyatt/
Research Description:

Research Associates are appointed positions for the purpose of developing scholarly competence, working under the supervision of a TSRI Faculty member.

Position Requirements: Must possess a doctoral degree. A pending doctoral degree may be considered with approval of the Principal Investigator.

Extensive virology/immunology/protein biochemistry experience to coordinate HIV envelope glycoprotein trimer protein expression and particulate array of with well-ordered, stable clade C/B/A or trimers. Biochemical experience to trouble shoot the free cysteine chemistry other protein conjugation methods.
EEO Statement: The Scripps Research Institute is an Equal Opportunity Employer. All qualified applicants are encouraged to apply and will receive consideration for employment without regard to race, color, religion, sex, sexual orientation, gender identity, national origin, disability, protected veteran status, or any other legally protected characteristic or status.
Principal Investigator Dr. Kristian Andersen
Department: Immunology and Microbial Science
Division: 3
Location: La Jolla, CA
Maildrop: SGM-300
Email application materials to: andersen@scripps.edu
URL: http://www.scripps.edu/andersen
Research Description:

Postdoc position in Pathogen discovery and surveillance.

The Andersen lab is working on diverse projects studying viral outbreaks using ‘Big Data’ genomics approaches and high-throughput technologies, such as next-generation sequencing. Our research is primarily focused on emerging viruses including Zika, Ebola, and Lassa. We use a combination of fieldwork in West Africa, technology development, and computational biology to investigate these viruses.

Tasks will include:

• Develop new technologies to better sequence and analyze viruses and other pathogens from different sample types.

• Perform independent experimental research exploring pathogen causality in human patients.

• Work directly with clinicians at Scripps hospitals to translate pathogen sequencing from bench to bedside.

• Conceive and implement assays and work with computational biologists to translate these models into testable experiments; analyze the data produced from these experiments

*Research Associates are appointed positions for the purpose of developing scholarly competence, working under the supervision of a TSRI Faculty member. These appointments are normally not renewed beyond a total of six years. Research Associates cannot apply for external funding either as a Principal Investigator or Co-Principal Investigator without prior approval from a Departmental Chair. Research Associates do not have consulting privileges.

Position Requirements: The Scripps Research Institute is currently seeking an experimental postdoc for the Andersen Lab working in the Department of Immunology and Microbial Sciences and Scripps Translational Science Institute. The successful candidate will join an interdisciplinary team of scientists, biologists, clinicians and computational scientists to apply experimental and computational tools to advance the state of the art in infectious disease genomics. We are looking for a dedicated individual who is interested in developing new technologies and novel analysis methods to realize the usage of pathogen genomics in a clinical setting. This research will help transform medicine with a direct impact on human health.

Requirements include:

• Ph.D. in molecular biology, RNA biology, or similar is required.

• Experience with next-generation sequencing datasets highly desired.

• Experience with computational data analysis using ‘Big Data’, including knowledge of statistical concepts is a plus.

• Programming skills in scripting languages such as Python/Perl, and analysis tools like MATLAB/R not required, but would be a plus.

• Strong interpersonal skills and the ability to work with and mentor junior scientists and students.

Interested candidates should submit their CV and the names and contact information for at least three references to jobs@andersen-lab.com. Please have referees email their references directly to references@andersen-lab.com.

EEO Statement: The Scripps Research Institute is an Equal Opportunity Employer. All qualified applicants are encouraged to apply and will receive consideration for employment without regard to race, color, religion, sex, sexual orientation, gender identity, national origin, disability, protected veteran status, or any other legally protected characteristic or status.
Principal Investigator Dr. Jiang Zhu
Department: Immunology and Microbial Science
Division: 3
Location: La Jolla, CA
Maildrop: IMM-306
Email application materials to: jiang@scripps.edu
Research Description:

Research Associates are appointed positions for the purpose of developing scholarly competence, working under the supervision of a TSRI Faculty member. These appointments are normally not renewed beyond a total of six years. Research Associates cannot apply for external funding either as a Principal Investigator or Co-Principal Investigator without prior approval from a Departmental Chair. Research Associates do not have consulting privileges.

Research projects including but not limited to antibody identification for important viral pathogens such as HIV-1, RSV, DENGUE and ZIKA using various approaches including phage/yeast display libraries, next-generation sequencing, and single B cell techniques. The identified antibodies will be characterized structurally and functionally to assist rational vaccine design or optimization of antibody therapeutics.

Position Requirements: We are seeking candidates with recently earned PhD in Biological Science (Molecular Biology, Protein Engineering) or a related field (Chemical Engineering, Biomedical Engineering). Candidates must have extensive experience in molecular biology, phage and/or yeast library-based antibody identification, and antibody engineering. Interested applicants should send a recent CV and three letters of reference to jiang@scripps.edu
EEO Statement: The Scripps Research Institute is an Equal Opportunity Employer. All qualified applicants are encouraged to apply and will receive consideration for employment without regard to race, color, religion, sex, sexual orientation, gender identity, national origin, disability, protected veteran status, or any other legally protected characteristic or status.
Principal Investigator Dr. Valente
Department: Immunology and Microbial Science
Location: Jupiter, FL
Email application materials to: svalente@scripps.edu
URL: http://www.scripps.edu/valente/people.html
Research Description:

Post-Doctoral Position available immediately
Department of Immunology and Microbial Sciences
The Scripps Research Institute in Jupiter, Florida


The Valente laboratory at The Scripps Research Institute – Florida is seeking exceptional candidates for a funded postdoctoral position, available immediately. The laboratory is mainly interested in HIV-1 latency; inhibitors of Tat-activated HIV-1 transcription; HIV-1 mRNA maturation and export; HIV capsid dimerization inhibitors (http://www.scripps.edu/valente/). Studies incorporate cellular and molecular virology, cell biology, primary cell culture, biochemistry, epigenetics and small molecule screening.

Position Requirements: Candidates must possess a Ph.D (or MD/PhD) in virology, molecular biology, cell biology, biochemistry, epigenetics, or immunology, with several international publications. The successful candidate will be expected to work in a BSL3 facility.
Interested candidates should send curriculum vitae, research interest, and the name and contact information of three references to Susana T. Valente, e-mail: svalente@scripps.edu

The Scripps Research institute-Florida (http://www.scripps.edu/florida/)
EEO Statement: The Scripps Research Institute is an Equal Opportunity Employer. All qualified applicants are encouraged to apply and will receive consideration for employment without regard to race, color, religion, sex, sexual orientation, gender identity, national origin, disability, protected veteran status, or any other legally protected characteristic or status.
Principal Investigator Philippe Gallay
Department: Immunology and Microbial Science
Division: 3
Location: La Jolla, CA
Maildrop: IMM-9
Email application materials to: gallay@scripps.edu
URL: http://www.scripps.edu/gallay/
Research Description:

This positions will be responsible for conducting both in vitro and in vivo constant and extended drug delivery studies in humanized mice for HIV-1 infection. Similar drug delivery implant approaches will be conducted for additional viral infections such as Dengue infection.

Research Associates are appointed positions for the purpose of developing scholarly competence, working under the supervision of a TSRI Faculty member. These appointments are normally not renewed beyond a total of six years. Research Associates cannot apply for external funding either as a Principal Investigator or Co-Principal Investigator without prior approval from a Departmental Chair. Research Associates do not have consulting privileges.

Position Requirements: Must possess a doctoral degree. A pending doctoral degree may be considered with approval of the Principal Investigator.

Interested candidates should submit their CV and the names and contact information for at least three references to gallay@scripps.edu.
EEO Statement: The Scripps Research Institute is an Equal Opportunity Employer. All qualified applicants are encouraged to apply and will receive consideration for employment without regard to race, color, religion, sex, sexual orientation, gender identity, national origin, disability, protected veteran status, or any other legally protected characteristic or status.
Principal Investigator Philippe Gallay
Department: Immunology and Microbial Science
Division: 3
Location: La Jolla, CA
Maildrop: IMM-9
Email application materials to: gallay@scripps.edu
URL: http://www.scripps.edu/gallay/
Research Description:

The position will be involved in the investigation of mechanisms of hepatitis B virus (HBV) replication both in vitro and in vivo as well as to identify mechanisms of action of new anti-HBV agents.

Research Associates are appointed positions for the purpose of developing scholarly competence, working under the supervision of a TSRI Faculty member. These appointments are normally not renewed beyond a total of six years. Research Associates cannot apply for external funding either as a Principal Investigator or Co-Principal Investigator without prior approval from a Departmental Chair. Research Associates do not have consulting privileges.

Position Requirements: Must possess a doctoral degree. A pending doctoral degree may be considered with approval of the Principal Investigator. Strong research experience in virology and cell culture highly preferred.

Interested candidates should submit their CV and the names and contact information for at least three references to gallay@scripps.edu.
EEO Statement: The Scripps Research Institute is an Equal Opportunity Employer. All qualified applicants are encouraged to apply and will receive consideration for employment without regard to race, color, religion, sex, sexual orientation, gender identity, national origin, disability, protected veteran status, or any other legally protected characteristic or status.
Principal Investigator Dr. Matthew Gill
Department: Metabolism and Aging
Location: Jupiter, FL
Email application materials to: mgill@scripps.edu
URL: https://www.scripps.edu
Research Description:

A post-doctoral position is available in the laboratory of Dr Matthew Gill in the Department of Metabolism & Aging at The Scripps Research Institute, Scripps Florida. Work in the lab is focused on characterizing signaling pathways in the nematode C. elegans that are involved in development and lifespan determination. This is being achieved by using an interdisciplinary approach combining genetic, genomic, biochemical and analytical chemistry approaches. The broader significance of this research is to further define the role of these signaling pathways in the etiology of aging and age-related disease and identify new targets for therapeutic intervention.

Position Requirements: Requirements: The position requires a PhD in a related scientific discipline with experience and publications demonstrating expertise in any of the following areas: genetics, molecular biology, protein expression & purification, lipid analysis or cell culture. Experience working with C. elegans and / or a background in aging research would be preferred but is not required.
To be considered, please send a cover letter describing your research interests, your CV, copies of representative publications, and a list of three individuals that can serve as references to Dr. Matthew Gill, mgill@scripps.edu.

For more information, visit www.scripps.edu. TSRI embraces diversity & recognizes it as being a key to our success. EOE/M/F/V/D
EEO Statement: The Scripps Research Institute is an Equal Opportunity Employer. All qualified applicants are encouraged to apply and will receive consideration for employment without regard to race, color, religion, sex, sexual orientation, gender identity, national origin, disability, protected veteran status, or any other legally protected characteristic or status.
Principal Investigator Dr. Sergio Catz
Department: Molecular and Experimental Medicine
Division: 3
Location: La Jolla, CA
Maildrop: MEM-280
Email application materials to: scatz@scripps.edu
URL: http://www.scripps.edu/catz/
Research Description:

A Postdoctoral research position is available immediately in the laboratory of Dr. Sergio D. Catz at the Department of Molecular and Experimental Medicine, The Scripps Research Institute, La Jolla. We are looking for a highly motivated scientist to contribute to our research projects designed to study the crosstalk between vesicular trafficking mechanisms and autophagy in the context of lysosomal storage disorders. The selected scientist will join our efforts to study the cellular and molecular mechanisms involved in the regulation of vesicular transport in proximal tubule cells, focusing on the roles of small Rab GTPases and their effectors in lysosomal exocytosis, endosomal maturation, lysosomal overload, ER stress and autophagy. The candidate will use a combination of molecular, cellular, genetic and drug-discovery approaches to study lysosomal function and chaperone-mediated autophagy using cells from genetically modified mouse models and human cellular models of lysosomal disease.

To apply please send your resume and cover letter to Dr. Sergio Catz at: scatz@scripps.edu

Position Requirements: A Ph.D. in cellular biology and or molecular biology is required.
EEO Statement: The Scripps Research Institute is an Equal Opportunity Employer. All qualified applicants are encouraged to apply and will receive consideration for employment without regard to race, color, religion, sex, sexual orientation, gender identity, national origin, disability, protected veteran status, or any other legally protected characteristic or status.
Principal Investigator Dr. Dennis Wolan
Department: Molecular and Experimental Medicine
Division: 3
Location: La Jolla, CA
Maildrop: MEM-L71
Email application materials to: wolan@scripps.edu
URL: http://www.scripps.edu/wolan/
Research Description:

A postdoctoral position is immediately available in the laboratory of Prof. Dennis Wolan (Department of Molecular and Experimental Medicine). The project requires a significant background in organic synthesis and will require the individual to learn and employ a variety of biophysical, in vitro assays, and cellular methods as platforms towards the discovery and iterative design of small molecule inhibitors of bacterial infections.

Position Requirements: Must possess a doctoral degree. A pending doctoral degree may be considered with approval of the Principal Investigator.

Successful candidates will work in a multidisciplinary research environment that greatly facilitates target discovery and lead compound discovery and optimization. TSRI provides a highly collaborative environment with outstanding synthetic and medicinal chemistry, chemical biology, structural biology and high-throughput screening facilities. Interested applicants should submit a CV, a brief statement of research experience, goals and contact information (email address and phone number) of three references to: wolan@scripps.edu.

Applicants should preferably have a Ph.D. in organic synthesis and drug discovery with knowledge of molecular biology, cellular biology and protein structure.
EEO Statement: The Scripps Research Institute is an Equal Opportunity Employer. All qualified applicants are encouraged to apply and will receive consideration for employment without regard to race, color, religion, sex, sexual orientation, gender identity, national origin, disability, protected veteran status, or any other legally protected characteristic or status.
Principal Investigator Dr. Richard Milner
Department: Molecular and Experimental Medicine
Division: 3
Location: La Jolla, CA
Maildrop: MEM-132
Email application materials to: rmilner@scripps.edu
Research Description:

A postdoctoral position is available in the Milner lab at the Scripps Research Institute (TSRI) in La Jolla, California, to work on vascular remodeling and blood-brain barrier (BBB) integrity in inflammatory demyelinating disease. The research will focus on the roles of specific extracellular matrix (ECM) receptors (integrins) to either promote vascular remodeling or stabilize BBB integrity. This study will employ the experimental autoimmune encephalomyelitis (EAE) mouse model of multiple sclerosis and will include the use of several endothelial-specific integrin-deficient transgenic mouse strains to define the roles of these integrins in regulating BBB integrity, vascular remodeling, vascular inflammation and activation of endothelial signaling pathways.

Position Requirements: The ideal candidates should have experience with the mouse EAE model and with standard genotyping and immuno-histochemical techniques. The position can begin as early as this May. Interested candidates should send a CV and a list of three potential referees to Dr. Richard Milner, rmilner@scripps.edu
EEO Statement: The Scripps Research Institute is an Equal Opportunity Employer. All qualified applicants are encouraged to apply and will receive consideration for employment without regard to race, color, religion, sex, sexual orientation, gender identity, national origin, disability, protected veteran status, or any other legally protected characteristic or status.
Principal Investigator Sandra Encalada
Department: Molecular and Experimental Medicine
Division: 3
Location: La Jolla, CA
Maildrop: MEM-215
Email application materials to: encalada@scripps.edu
URL: http://www.scripps.edu/encalada/
Research Description:

A postdoctoral position is available in the Encalada Laboratory at The Scripps Research Institute in La Jolla, California, USA, in the areas of neurodegeneration, aging, and intracellular transport. Our lab is interested in characterizing the mechanisms of regulation of molecular motor-driven transport in neurons and the role that defective transport plays in neurodegeneration and aging, with an emphasis on prion, Alzheimer’s and other aggregation-associated degenerative diseases. We use a combination of cell biology, genetics, biochemistry, and high-resolution quantitative microscopy in mammalian neurons and in C. elegans to address these research areas, and possible projects include characterization of model organism models of neurodegenerative diseases.

Position Requirements: You are about to complete your PhD or have completed your PhD within the last year in cell biology, genetics, neurobiology, molecular biology, biophysics, or related field.
Preferred candidates are highly motivated, independent, with outstanding written and oral communication skills, and ideally with peer-reviewed publications. Plus research experience with C. elegans and/or cell culture, and with light microscopy is preferred but not required.

Interested candidates please send a CV with a list of publications, a brief statement of your previous research expertise, future interests, and the contact information of three references to Sandra Encalada at encalada@scripps.edu. For more information also please consult our website at http://www.scripps.edu/encalada/encalada/HOME.html
EEO Statement: The Scripps Research Institute is an Equal Opportunity Employer. All qualified applicants are encouraged to apply and will receive consideration for employment without regard to race, color, religion, sex, sexual orientation, gender identity, national origin, disability, protected veteran status, or any other legally protected characteristic or status.
Principal Investigator Ted Kamenecka
Department: Molecular Therapeutics
Location: Jupiter, FL
Email application materials to: KOBrien@scripps.edu
URL: https://www.scripps.edu/research/faculty/kamenecka
Research Description:

Postdoctoral positions in Medicinal Chemistry are available in the Kamenecka group in The Department of Molecular Therapeutics at the Scripps Research Institute, Florida campus (for more information please see: https://www.scripps.edu/research/faculty/kamenecka). Successful candidates will have a proven track record of publishing in high impact journals and extensive experience in organic synthesis and/or medicinal chemistry, and can work successfully as a member of a team. These full-time lab positions are available starting August 2016.

Position Requirements: Extensive Ph.D. graduate work in multi-step organic synthesis is required, with good laboratory skills and familiarity with modern synthetic techniques and instrumentation (HPLC-MS, HPLC, NMR, chromatography). Strong candidates may also have knowledge and experience in heterocyclic and medicinal chemistry and/or structure-based drug design. Excellent communication skills and interpersonal skills necessary to thrive in a fast-paced team-oriented environment are also required.

Please send CV, research summary, and 3 references to: Kate O’Brien, Scripps Florida, 130 Scripps Way #2A1, Jupiter, FL 33458; or preferably by e-mail: KOBrien@scripps.edu (please include “medicinal chemistry postdoctoral recruiting” in the subject line).

EEO Statement: The Scripps Research Institute is an Equal Opportunity Employer. All qualified applicants are encouraged to apply and will receive consideration for employment without regard to race, color, religion, sex, sexual orientation, gender identity, national origin, disability, protected veteran status, or any other legally protected characteristic or status.
Principal Investigator Dr. Seth Tomchik
Department: Neuroscience
Location: Jupiter, FL
Email application materials to: stomchik@scripps.edu
URL: http://www.scripps.edu/tomchik/
Research Description:

A postdoctoral position is available in the lab of Dr. Seth M. Tomchik in the department of Neuroscience. We are interested in how dopaminergic circuits modulate the plasticity that underlies learning (e.g., Boto et al 2014, Curr Biol 24: 822-831). The next major challenge is to decipher how these pathways, and others, are activated during biologically relevant events in vivo, how neuronal circuit properties are modified as a result, how this plasticity underlies learned behaviors, and how these processes are disrupted in disease models.

We are seeking a postdoctoral fellow to dissect the role of neuromodulatory circuits in modulating learned behaviors in Drosophila. The project will involve in vivo imaging, optogenetic/thermogenetic stimulation of discrete neuronal circuits, as well as molecular/genetic and behavioral approaches in both normal animals and disease models. The anticipated start date will be as early as Spring 2017, though the position will remain open until filled.

Position Requirements: Basic Qualifications:
A Ph.D. or M.D. is required, with appropriate experience in a related discipline.

Preferred Qualifications:
The chosen candidate will have a track record of productivity and research excellence, peer-reviewed publications, and relevant research interests. Highly motivated candidates from a variety of backgrounds and experience will be considered. Desirable experience could be in one or more of the following areas: imaging, electrophysiology, genetics, molecular/cell biology, or behavioral neuroscience.

Interested candidates should submit: a cover letter (including experience, research and career goals, and interests as related to our research), Curriculum Vitae, and complete contact information for at least three professional references to:

Dr. Seth M. Tomchik, Assistant Professor
Department of Neuroscience
The Scripps Research Institute, Scripps Florida
130 Scripps Way, 3C2
Jupiter, Florida, 33458
stomchik@scripps.edu



EEO Statement: The Scripps Research Institute is an Equal Opportunity Employer. All qualified applicants are encouraged to apply and will receive consideration for employment without regard to race, color, religion, sex, sexual orientation, gender identity, national origin, disability, protected veteran status, or any other legally protected characteristic or status.
Principal Investigator Dr. Damon Page
Department: Neuroscience
Location: Jupiter, FL
Email application materials to: paged@scripps.edu
URL: http://www.scripps.edu/page/
Research Description:

A postdoctoral position is available in the Page laboratory in the Department of Neuroscience at The Scripps Research Institute in Jupiter, Florida to investigate mechanisms of neurogenesis & gliogenesis, axon/dendrite growth and synaptic connectivity in the developing mouse cerebral cortex. A major goal of this project is to understand the influence of genetic risk factors for autism and other neurodevelopmental disorders on these processes at the molecular/cellular, circuit and behavioral levels. For information about the laboratory, please visit: www.scripps.edu/page/.

Position Requirements: In addition to a PhD, highly motivated candidates with expertise in developmental biology, genetics, molecular/cell biology, imaging or behavioral neuroscience are encouraged to apply.

Interested candidates should send a cover letter, CV and contact details for three references to Damon Page, Ph.D., email: paged@scripps.edu.
EEO Statement: The Scripps Research Institute is an Equal Opportunity Employer. All qualified applicants are encouraged to apply and will receive consideration for employment without regard to race, color, religion, sex, sexual orientation, gender identity, national origin, disability, protected veteran status, or any other legally protected characteristic or status.
Principal Investigator Dr. Srini Subramaniam
Department: Neuroscience
Location: Jupiter, FL
Email application materials to: ssubrama@scripps.edu
URL: http://www.scripps.edu/subramaniam/index.html
Research Description:

A post-doctoral position is available immediately in the Department of Neuroscience, at the Scripps Research Institute-Florida (TSRI-Florida), to study the mechanisms of neurodegeneration. Candidate must hold a PhD degree and have experience in cell signaling, mouse genetics, rodent surgery, stereotaxic injection, anatomy, histology, microscopy and biochemistry.

Position Requirements: Candidate must be highly motivated and have the ability to work in a team. Position is open for two years with potentials of further extension. For the details of the research work, please visit http://www.scripps.edu/subramaniam/index.html
TSRI is an excellent medical research facility that focuses on research and education in the biomedical sciences, making it among the largest private, non-profit biomedical research organizations in the world. Successful candidates will join an exciting scientific community of drug discovery and neuroscience while enjoying natural beauty of Florida. https://www.scripps.edu/florida/
Please send your cover letter and resume with reference details to: Srini Subramaniam: ssubrama@scripps.edu
EEO Statement: The Scripps Research Institute is an Equal Opportunity Employer. All qualified applicants are encouraged to apply and will receive consideration for employment without regard to race, color, religion, sex, sexual orientation, gender identity, national origin, disability, protected veteran status, or any other legally protected characteristic or status.
Principal Investigator Dr. Gavin Rumbaugh
Department: Neuroscience
Location: Jupiter, FL
Email application materials to: grumbaug@scripps.edu
URL: http://rumbaugh.florida.scripps.edu/Rumbaugh_Lab/Gavin.html
Research Description:

We are seeking to fill a federally funded postdoctoral position at the Department of Neuroscience, Scripps Research Institute located in Jupiter, Florida. The position will focus on the study of neural network structure and function in mouse models of intellectual disability, autism spectrum disorder and epilepsy.

Position Requirements: Successful candidates will have recently received a Ph.D. degree, have a strong publication record and have prior multi-photon imaging or whole-cell patch clamp experience. Computer programming skills (e.g. MatLAB) are also desired. Please visit the laboratory website at:

http://rumbaugh.florida.scripps.edu/Rumbaugh_Lab/Gavin.html

To apply, please send CV, brief description of research interests and contact information of references to Dr. Gavin Rumbaugh at grumbaug@scripps.edu. The Scripps Research Institute provides an outstanding intellectual environment and access to a wide range of cutting edge technologies.
The Scripps Research Institute is an Equal Opportunity Employer. All qualified applicants are encouraged to apply and will receive consideration for employment without regard to race, color, religion, sex, sexual orientation, gender identity, national origin, disability, protected veteran status, or any other legally protected characteristic or status.






EEO Statement: The Scripps Research Institute is an Equal Opportunity Employer. All qualified applicants are encouraged to apply and will receive consideration for employment without regard to race, color, religion, sex, sexual orientation, gender identity, national origin, disability, protected veteran status, or any other legally protected characteristic or status.
Principal Investigator Dr. Ron Davis
Department: Neuroscience
Location: Jupiter, FL
Email application materials to: rdavis@scripps.edu
URL: http://www.scripps.edu/research/faculty/davis
Research Description:

Currently seeking Postdoctoral Research Associates who will work on projects involving small molecule screening against molecular or phenotypic targets for the purpose of identifying new probes and lead compounds for neuroprotection and cognitive enhancement.

Position Requirements: PhD in a relevant scientific discipline and experience with research projects that employ diverse techniques and address questions that range from the molecular to the behavioral is required.

To be considered, submit Curriculum Vitae and complete contact information for at least three professional references as a single PDF file, to rdavis@scripps.edu.

EEO Statement: The Scripps Research Institute is an Equal Opportunity Employer. All qualified applicants are encouraged to apply and will receive consideration for employment without regard to race, color, religion, sex, sexual orientation, gender identity, national origin, disability, protected veteran status, or any other legally protected characteristic or status.
Principal Investigator Baoji Xu
Department: Neuroscience
Location: Jupiter, FL
Email application materials to: bxu@scripps.edu
URL: http://www.scripps.edu/florida/neuro/bxu.html
Research Description:

Postdoctoral positions are available to work on projects investigating synaptic plasticity, control of synaptic protein synthesis, and central control of energy balance in mice using genetic, cellular, molecular, viral, histological, physiological, and behavioral approaches. These research projects are related to many diseases, such as autism spectrum disorders, depression, obesity, and diabetes. The successful candidates also have opportunities to work on translational projects related to Huntington’s disease and Alzheimer’s disease.

Position Requirements: In addition to a PhD in a related discipline, candidates should be highly motivated and have a strong record of productivity. Those with a strong background in electrophysiology or medicinal chemistry are particularly encouraged to apply. Interested candidates should send a cover letter, curriculum vitae and contact information for three references to: bxu@scripps.edu.
EEO Statement: The Scripps Research Institute is an Equal Opportunity Employer. All qualified applicants are encouraged to apply and will receive consideration for employment without regard to race, color, religion, sex, sexual orientation, gender identity, national origin, disability, protected veteran status, or any other legally protected characteristic or status.
Principal Investigator Kirill Martemyanov
Department: Neuroscience
Location: Jupiter, FL
Email application materials to: kirill@scripps.edu
URL: http://www.scripps.edu/martemyanov
Research Description:

Molecular and Cellular Neurobiology of GPCR Systems

An NIH funded postdoctoral position is available within the Jupiter, FL campus to study molecular, cellular and behavioral aspects of neuronal signaling. We are looking for an energetic colleague with keen interest in science and solid background in the areas of physiology, molecular and cell biology.

The laboratory is interested in delineating mechanisms by which GPCR pathways control reward behavior, vision and provide neural control of the cardiac function. It is expected that the project will contribute to our understanding of the neuropsychiatric diseases, drug addiction and vision loss while focusing on the discovery of the fundamental neurobiological principles. Multidisciplinary approach integrating behavioral characterization of genetic mouse models with live cell imaging, biochemical analysis of signaling reactions and discovery of novel interactions by mass-spectrometry assisted proteomics is envisioned. For details visit the website of the laboratory at http://www.scripps.edu/martemyanov.

Position Requirements: Requirements: PhD in a related scientific discipline and experience with electrophysiological approaches and/or genetic mouse models for investigation of cardiovascular function is required. An energetic colleague with keen interest in science and solid background in the areas of physiology, molecular and cell biology is strongly desired.

To be considered, please send CV, brief description of research interests and contact information of references to Dr. Kirill Martemyanov at kirill@scripps.edu. Both experienced scientists and recent graduates are encouraged to apply. The PI is committed to the career development of trainees.
EEO Statement: The Scripps Research Institute is an Equal Opportunity Employer. All qualified applicants are encouraged to apply and will receive consideration for employment without regard to race, color, religion, sex, sexual orientation, gender identity, national origin, disability, protected veteran status, or any other legally protected characteristic or status.
Principal Investigator Ron Davis
Department: Neuroscience
Location: Jupiter, FL
Email application materials to: rdavis@scripps.edu
URL: http://www.scripps.edu/research/faculty/davis
Research Description:

Currently seeking Postdoctoral Research Associates who will work on projects involving the molecular and cellular biology of memory formation in Drosophila and the mouse using genetic, molecular, cellular, anatomical and behavioral approaches. In addition, selected individuals may perform translational research on mood disorders and Alzheimer's disease.

Position Requirements: PhD in a relevant scientific discipline and experience with research projects that employ diverse techniques and address questions that range from the molecular to the behavioral is required.

To be considered, submit Curriculum Vitae and complete contact information for at least three professional references as a single PDF file, to rdavis@scripps.edu.
EEO Statement: The Scripps Research Institute is an Equal Opportunity Employer. All qualified applicants are encouraged to apply and will receive consideration for employment without regard to race, color, religion, sex, sexual orientation, gender identity, national origin, disability, protected veteran status, or any other legally protected characteristic or status.
Principal Investigator Dr. Richard Lerner
Department: Cell and Molecular Biology
Division: 3
Location: La Jolla, CA
Maildrop: MB-10
Email application materials to: kyungmoo@scripps.edu
Research Description:

Research Associates are appointed positions for the purpose of developing scholarly competence, working under the supervision of a TSRI Faculty member.

Lab information:
We first published the concept of combinatorial antibody libraries in 1989 (Huse et al.). Thus, we are well versed in antibody construction and selection. In addition, we have constructed lentiviral antibody libraries so phenotypic screens can be carried out. We have published several papers on antibodies that induce stem cells to differentiate unique cell fate such as neuron, megakaryocyte, dendritic cells and natural killer cells using this approach (1-4).
Recently, we have established a novel lentiviral cytokine library and applied this to human stem cell biology. We found potent cytokines that regulate the differentiation of stem cells and novel mechanisms. Based on this newly developed method, we would like to discover new potent cytokine pathways in other biological systems such as immune checkpoint regulation in T cells, retinal vascularization etc.

There are opportunities for studies within any of the above research lines, depending on the background and interests of the applicant.

Please send resume & cover letter to Dr. Kyungmoo Yea @ kyungmoo@scripps.edu &
Cc: fiona@scripps.edu


Position Requirements: A Ph.D. in Biology or in other disciplines of relevance to the project is required. The candidate should have a strong experimental background in cell biology or stem cell biology. She/he should be proactive and productive, and have a track record of successful project completion.
EEO Statement: The Scripps Research Institute is an Equal Opportunity Employer. All qualified applicants are encouraged to apply and will receive consideration for employment without regard to race, color, religion, sex, sexual orientation, gender identity, national origin, disability, protected veteran status, or any other legally protected characteristic or status.
Principal Investigator Claudio Joazeiro
Department: Cell and Molecular Biology
Division: 3
Location: La Jolla, CA
Maildrop: CB-163
Email application materials to: joazeiro@scripps.edu
URL: http://www.scripps.edu/joazeiro/
Research Description:

Research in the lab investigates the function of E3 ubiquitin ligases in biology and disease (Deshaies & Joazeiro, 2009. Annu Rev Biochem. 78:399-434). The position available is to elucidate the mechanism of action of the Listerin E3 in a novel pathway of ribosome-associated protein quality control, and/or how defects in Listerin function cause neurodegeneration. We had previously reported on a new mouse model of ALS/motor neuron disease caused by mutation of Listerin/Ltn1, whose function was unknown at the time (Chu et al. 2009. PNAS 106:2097-103). Listerin is conserved in eukaryotes, so we utilized S. cerevisiae to elucidate its function and mechanism of action, and found that Listerin is associated with ribosomes and mediates quality control of aberrant nascent proteins (Bengtson & Joazeiro 2010. Nature 467:470-3). Our lab is now undertaking different approaches to continue studying Listerin, including biochemistry, yeast genetics, structural biology, mammalian tissue culture, and gene-disease association studies using ALS patient samples. We are also well positioned to uncover novel molecular mechanisms underlying neurodegeneration by applying the discoveries we make with these approaches to studies on the Listerin mutant mouse model. There are opportunities for studies along any of the above research lines, depending on the background and interests of the applicant.

Research Associates are appointed positions for the purpose of developing scholarly competence, working under the supervision of a TSRI Faculty member. These appointments are normally not renewed beyond a total of six years. Research Associates cannot apply for external funding either as a Principal Investigator or Co-Principal Investigator without prior approval from a Departmental Chair. Research Associates do not have consulting privileges.

Position Requirements: A Ph.D. in Biology or in other disciplines of relevance to the project is required. The candidate should have strong conceptual and experimental background in related areas. He/she should be proactive and productive, and have track record of successful project completion.

Interested applicants, please send a paragraph on current and future research interests, and the names and contact information of three references to joazeiro@scripps.edu.
EEO Statement: The Scripps Research Institute is an Equal Opportunity Employer. All qualified applicants are encouraged to apply and will receive consideration for employment without regard to race, color, religion, sex, sexual orientation, gender identity, national origin, disability, protected veteran status, or any other legally protected characteristic or status.
Principal Investigator Dr. Qinghai Zhang
Department: Integrative Structural and Computational Biology
Division: 3
Location: La Jolla, CA
Maildrop: MB-23
Email application materials to: qinghai@scripps.edu
URL: http://www.scripps.edu/zhang/
Research Description:

Research Associates are appointed positions for the purpose of developing scholarly competence, working under the supervision of a TSRI Faculty member.

Postdoctoral position is open in the Zhang lab at The Scripps Research Institute. The main duty of the candidate is to design, synthesize and characterize small molecules targeting a drug transporter in cancer cells. The drug development involves structure-based design, optimization of known anticancer drugs, functional assay, cell-based screening, and co-crystal structural determinations with the drug target. The project is funded by NIH and involves multidisciplinary collaborations.

Please send your CV, a research summary, and list of 3 references to Dr. Qinghai Zhang at qinghai@scripps.edu.

Position Requirements: Must possess a doctoral degree. A pending doctoral degree may be considered with approval of the Principal Investigator.

Requirements: Ph. D. in organic chemistry is required. Strong background in organic synthesis is a must. Experience in mammalian cell culture is desired but not necessary. The candidate should possess excellent communication and writing skills.
EEO Statement: The Scripps Research Institute is an Equal Opportunity Employer. All qualified applicants are encouraged to apply and will receive consideration for employment without regard to race, color, religion, sex, sexual orientation, gender identity, national origin, disability, protected veteran status, or any other legally protected characteristic or status.
Principal Investigator Dr. Takanori Otomo
Department: Integrative Structural and Computational Biology
Division: 3
Location: La Jolla, CA
Maildrop: MB-104
Email application materials to: totomo@scripps.edu
URL: http://www.scripps.edu/otomo
Research Description:

The Otomo lab studies structural and biochemical mechanisms underlying and regulating autophagy. Autophagy is the bulk degradation-recycling program that plays crucial roles in maintenance of cellular homeostasis and damage control. The major focus in our research is to understand how a membrane-bound vesicle called autophagosome sequesters cytoplasmic materials into lysosomes for degradation. We aim to achieve our goal by characterizing autophagy-related (Atg) proteins and reconstituting the key steps in autophagosome formation. We use a combination of biochemical, structural and cell biological strategies. Our major structural tools are X-ray crystallography, NMR spectroscopy, and electron microscopy.

Position Requirements: Must possess a doctoral degree. A pending doctoral degree may be considered with approval of the Principal Investigator.

Requirements: A strong commitment to science, an interest in the research topic, and excellent communication skills, are absolutely required. Expertise in protein biochemistry and familiarities to structural methods are crucial. Priority will be given to candidates that have earned PhD recently and identified potential fellowship opportunities. For consideration, please send CV, summary of research accomplishments and interests, and three professional references to totomo@scripps.edu.
EEO Statement: The Scripps Research Institute is an Equal Opportunity Employer. All qualified applicants are encouraged to apply and will receive consideration for employment without regard to race, color, religion, sex, sexual orientation, gender identity, national origin, disability, protected veteran status, or any other legally protected characteristic or status.
Principal Investigator Andrew Su
Department: Integrative Structural and Computational Biology
Division: 3
Location: La Jolla, CA
Maildrop: MEM-216
Email application materials to: asu@scripps.edu
URL: http://sulab.org
Research Description:

The Su Lab is recruiting for multiple postdoctoral associates in bioinformatics and computational biology. These positions will participate in a wide variety of genomics and genetics analyses in close collaboration with world-class experimental researchers at Scripps. Example projects include N-of-1 cancer genomics, osteoarthritis, cystic fibrosis, and microbiomics.

Applicants should have a Ph.D. in bioinformatics or biology, and as well as a good foundation in some form of computer programming and statistics. Past experience working with modern genomics data (next gen sequencing, microarrays, proteomics, etc.) is highly desirable.

More information about the lab's interests can be found at http://sulab.org.

Interested individuals should send their CV, a letter describing research interests, and the names/contact information of 3 references to Dr. Andrew Su at: asu@scripps.edu.

Position Requirements: Must possess a doctoral degree. A pending doctoral degree may be considered with approval of the Principal Investigator.
EEO Statement: The Scripps Research Institute is an Equal Opportunity Employer. All qualified applicants are encouraged to apply and will receive consideration for employment without regard to race, color, religion, sex, sexual orientation, gender identity, national origin, disability, protected veteran status, or any other legally protected characteristic or status.
Principal Investigator Andrew Su
Department: Integrative Structural and Computational Biology
Division: 3
Location: La Jolla, CA
Maildrop: MEM-216
Email application materials to: asu@scripps.edu
URL: http://sulab.org
Research Description:

The Su Lab is currently recruiting for a postdoctoral associate in bioinformatics software development. This position will participate in the design and development of the Gene Wiki, BioGPS, and/or GeneGames.org. All of these applications developed by our lab embrace the principles of community intelligence and crowdsourcing.

Applicants should have a Ph.D. in bioinformatics or biology, and as well as a good foundation in some form of computer programming and statistics. Past experience working with modern genomics data (next gen sequencing, microarrays, proteomics, etc.) is highly desirable.

More information about the lab's interests can be found at http://sulab.org.

Interested individuals should send their CV, a letter describing research interests, and the names/contact information of 3 references to Dr. Andrew Su at: asu@scripps.edu.

Position Requirements: Must possess a doctoral degree. A pending doctoral degree may be considered with approval of the Principal Investigator.
EEO Statement: The Scripps Research Institute is an Equal Opportunity Employer. All qualified applicants are encouraged to apply and will receive consideration for employment without regard to race, color, religion, sex, sexual orientation, gender identity, national origin, disability, protected veteran status, or any other legally protected characteristic or status.
Principal Investigator Pietro Sanna, M.D.
Department: Molecular and Cellular Neuroscience
Division: 3
Location: La Jolla, CA
Maildrop: SP30-2300
Email application materials to: psanna@scripps.edu
Research Description:

Research Associates are appointed positions for the purpose of developing scholarly competence, working under the supervision of a TSRI Faculty member.

A NIH-funded post-doctoral position is available immediately for a motivated individual to join a dynamic multidisciplinary research team at The Scripps Research Institute to study the effects of alcohol and drugs of abuse with electrophysiological methods.

Position Requirements: Must possess a doctoral degree. A pending doctoral degree may be considered with approval of the Principal Investigator.

A background in bio- physics is preferred.

Send CVs & references to psanna@scripps.edu.
EEO Statement: The Scripps Research Institute is an Equal Opportunity Employer. All qualified applicants are encouraged to apply and will receive consideration for employment without regard to race, color, religion, sex, sexual orientation, gender identity, national origin, disability, protected veteran status, or any other legally protected characteristic or status.
Principal Investigator Pietro Sanna, M.D.
Department: Molecular and Cellular Neuroscience
Location: La Jolla, CA
Maildrop: SP30-2300
Email application materials to: psanna@scripps.edu
Research Description:

AA NIH-funded post-doctoral position is available for a motivated individuals to join a multidisciplinary effort to study the neurobiological bases of drug addiction. The project will combine behavioral pharmacology, gene expression assay by RNA-Seq, and other molecular biological techniques.

Position Requirements: Must possess a doctoral degree. A pending doctoral degree may be considered with approval of the Principal Investigator.

Successful candidates will be creative, highly motivated, able to work semi-independently, and have a strong background in behavioral neuroscience.

Send CVs & references to psanna@scripps.edu
EEO Statement: The Scripps Research Institute is an Equal Opportunity Employer. All qualified applicants are encouraged to apply and will receive consideration for employment without regard to race, color, religion, sex, sexual orientation, gender identity, national origin, disability, protected veteran status, or any other legally protected characteristic or status.
Principal Investigator Dr. Anton Maximov
Department: Molecular and Cellular Neuroscience
Division: 3
Location: La Jolla, CA
Maildrop: DNC-216
Email application materials to: amaximov@scripps.edu
URL: http://www.scripps.edu/maximov/index.html
Research Description:

The Maximov laboratory at the Scripps Research Institute (TSRI) is seeking motivated postdoctoral fellows with prior experience in electrophysiology. Our group uses a multidisciplinary approach to study the molecular mechanisms of synapse formation and structural plasticity in the mammalian forebrain. Successful candidates will be expected to drive independent projects, and will have an opportunity to learn contemporary genetic, imaging and neurobehavioral techniques through collaborations with other lab members.

TSRI is one of the world’s top biomedical research institutes. Our laboratory is a part of the TSRI Dorris Neuroscience Center (DNC) in La Jolla that brings together investigators with interests in neural circuit formation, synaptic plasticity, sensory processing, learning and memory, and aging. New group members will have an excellent opportunity for career development in a highly collaborative environment. To learn more about TSRI, DNC and our lab, please visit:
http://www.scripps.edu
https://www.scripps.edu/research/dorriscenter/
http://www.scripps.edu/maximov/index.html

Position Requirements: • PhD in neuroscience, biophysics or other relevant scientific discipline.
• Strong background in electrophysiological measurements of neuronal excitability and/or synaptic transmission.
• First-author publications (or manuscripts in press)
• Keen interest in leading an exciting research direction, and ability to work in a team-oriented environment.
• While not required, experience with mouse models, viral injections and optogenetic stimulation will be helpful.

Please apply with your CV, a brief statement of research interests, and the names of 2-3 supervisors and mentors who can be contacted for references.

Applications should be sent as single PDF files to: amaximov@scripps.edu
EEO Statement: The Scripps Research Institute is an Equal Opportunity Employer. All qualified applicants are encouraged to apply and will receive consideration for employment without regard to race, color, religion, sex, sexual orientation, gender identity, national origin, disability, protected veteran status, or any other legally protected characteristic or status.
Principal Investigator Pietro Sanna, M.D.
Department: Molecular and Cellular Neuroscience
Division: 3
Location: La Jolla, CA
Maildrop: SP30-2300
Email application materials to: psanna@scripps.edu
Research Description:

A post-doctoral position is available immediately for a motivated individual to join a dynamic multidisciplinary research team at The Scripps Research Institute to study gene regulation
with a systems biology strategy and high-throughput methods.

This NIH-funded position offers a competitive pay and benefits package.

Research Associates are appointed positions for the purpose of developing scholarly competence, working under the supervision of a TSRI Faculty member. These appointments are normally not renewed beyond a total of six years. Research Associates cannot apply for external funding either as a Principal Investigator or Co-Principal Investigator without prior approval from a Departmental Chair. Research Associates do not have consulting privileges.

Position Requirements: Must possess a doctoral degree. A pending doctoral degree may be considered with approval of the Principal Investigator. Successful candidates will be creative, highly motivated, able to work semi-independently, and have a strong background in computational methods, genomics, biophysics or related areas.

Interested applicants should submit a CV and contact information for three references to psanna@scripps.edu.
EEO Statement: The Scripps Research Institute is an Equal Opportunity Employer. All qualified applicants are encouraged to apply and will receive consideration for employment without regard to race, color, religion, sex, sexual orientation, gender identity, national origin, disability, protected veteran status, or any other legally protected characteristic or status.